Renal histopathology after mixed liquor consumption in Wistar rat

نویسندگان

چکیده

In Indonesia illegal traditional liquor mostly contain ethanol and methanol some of called cukrik (mixed liquor), Misuse mixed can lead to intoxication may death. Several studies have shown its effect on kidney damage. This study is analyzing the (ethanol methanol) histopathological damage male Wistar rat kidney. was experimental laboratories using a post-test only control group design. We are 28 wistar rats that were divided into four groups, each consisting 7 rats. Group (C) given 4 mL distilled water; groups P1, P2, P3 1ml, 2 ml, ml in orally for 14 days. Mixed alcohol contains 4% 20% ethanol. Examination features carried out by identifying glomerular cells, tubular interstitial with HE (Hematoxylin Eosin) stainning EGTI (Endothelial, Glomerular, Tubular, Interstitial) scoring. Data analyze kruskal wallis Mann whitney test. With confidence level p<0,01. examination there significant differences p<0,01, no found instrestitial Consumption produced image rats' kidneys, but visible interstitials cell. higher consumption will make heavier.

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ژورنال

عنوان ژورنال: GSC biological and pharmaceutical sciences

سال: 2022

ISSN: ['2581-3250']

DOI: https://doi.org/10.30574/gscbps.2022.20.3.0354